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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF4B
All Species:
24.85
Human Site:
Y557
Identified Species:
36.44
UniProt:
Q2VIQ3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2VIQ3
NP_001092763.1
1234
140035
Y557
L
Q
P
I
Q
F
Q
Y
Q
D
N
I
K
N
L
Chimpanzee
Pan troglodytes
XP_518055
1227
139177
Y557
L
Q
P
I
Q
F
Q
Y
Q
E
K
V
I
N
L
Rhesus Macaque
Macaca mulatta
XP_001084213
1234
139742
Y557
L
Q
P
I
Q
Y
Q
Y
Q
D
N
I
K
E
L
Dog
Lupus familis
XP_549061
1234
139874
Y558
L
Q
P
I
H
F
Q
Y
Q
D
N
I
K
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P33174
1231
139533
Y558
L
Q
P
I
Q
F
Q
Y
Q
D
N
I
K
N
L
Rat
Rattus norvegicus
Q7M6Z5
1394
158861
E655
D
E
D
S
E
G
Q
E
K
P
R
V
R
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
Y563
L
E
P
I
Q
S
Q
Y
Q
T
N
I
K
D
L
Frog
Xenopus laevis
Q91784
1226
138905
Y560
L
E
P
I
Q
S
E
Y
L
N
N
I
K
H
L
Zebra Danio
Brachydanio rerio
Q58G59
1363
154819
G664
I
P
Q
G
P
F
G
G
T
R
T
A
L
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
I226
H
S
S
R
S
H
A
I
F
M
I
K
I
E
M
Honey Bee
Apis mellifera
XP_395595
1064
123475
P500
S
M
E
E
I
C
S
P
D
S
L
D
D
F
D
Nematode Worm
Caenorhab. elegans
P46873
699
78760
E141
S
Y
L
E
I
Y
N
E
E
V
R
D
L
L
G
Sea Urchin
Strong. purpuratus
P46872
699
78679
L141
E
Q
E
N
V
R
F
L
V
R
V
S
Y
L
E
Poplar Tree
Populus trichocarpa
XP_002302432
1055
118553
E484
K
R
S
L
H
S
I
E
S
P
D
Y
Q
M
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200901
1294
145204
L558
Q
E
K
L
D
M
E
L
K
E
L
D
K
R
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
V370
I
V
N
L
E
S
E
V
Q
V
W
R
G
G
E
Conservation
Percent
Protein Identity:
100
97.9
90.9
91
N.A.
83.6
26.4
N.A.
N.A.
71.3
66.6
25.1
N.A.
27.2
36.8
25.6
27.4
Protein Similarity:
100
98.8
94
94.7
N.A.
90.3
47.2
N.A.
N.A.
83.7
80.1
44.1
N.A.
41
55.8
38.5
38.4
P-Site Identity:
100
73.3
86.6
93.3
N.A.
100
6.6
N.A.
N.A.
73.3
60
6.6
N.A.
0
0
0
6.6
P-Site Similarity:
100
86.6
93.3
93.3
N.A.
100
46.6
N.A.
N.A.
86.6
86.6
13.3
N.A.
6.6
0
13.3
6.6
Percent
Protein Identity:
31.9
N.A.
N.A.
30.6
N.A.
26.6
Protein Similarity:
50
N.A.
N.A.
49.1
N.A.
44
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
26.6
N.A.
N.A.
46.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
7
0
0
0
7
25
7
19
7
7
7
% D
% Glu:
7
25
13
13
13
0
19
19
7
13
0
0
0
13
13
% E
% Phe:
0
0
0
0
0
32
7
0
7
0
0
0
0
7
0
% F
% Gly:
0
0
0
7
0
7
7
7
0
0
0
0
7
7
13
% G
% His:
7
0
0
0
13
7
0
0
0
0
0
0
0
7
0
% H
% Ile:
13
0
0
44
13
0
7
7
0
0
7
38
13
0
0
% I
% Lys:
7
0
7
0
0
0
0
0
13
0
7
7
44
0
0
% K
% Leu:
44
0
7
19
0
0
0
13
7
0
13
0
13
13
50
% L
% Met:
0
7
0
0
0
7
0
0
0
7
0
0
0
7
7
% M
% Asn:
0
0
7
7
0
0
7
0
0
7
38
0
0
25
0
% N
% Pro:
0
7
44
0
7
0
0
7
0
13
0
0
0
7
0
% P
% Gln:
7
38
7
0
38
0
44
0
44
0
0
0
7
0
7
% Q
% Arg:
0
7
0
7
0
7
0
0
0
13
13
7
7
7
7
% R
% Ser:
13
7
13
7
7
25
7
0
7
7
0
7
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
7
7
0
0
0
0
% T
% Val:
0
7
0
0
7
0
0
7
7
13
7
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
0
0
0
13
0
44
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _